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What is Great Mullein and Why Does It Matter?

Great Mullein is an Uncommon Topside Material used primarily for crafting medical items. In terms of gameplay, it is lightweight (0.25 weight per unit) and stacks up to 15 in your inventory. You’ll need it for creating:

Antiseptic (requires 2× Great Mullein + 10× Chemicals at a Refiner 2)

Herbal Bandages (requires 1× Great Mullein + 1× Durable Cloth at Medical Lab 1)

Herbal Bandages via Traveling Tinkerer skill (requires 1× Great Mullein + 14× Fabric)

In practical terms, this means if you plan to run missions where medkits are vital, stocking up on Great Mullein first will save a lot of trips back to town or your base.

Where Can I Find Great Mullein?

There are three main sources:

Harvesting from Nature – You’ll find the Great Mullein plant scattered in open areas across the Topside. Approaching the plant and pressing your interact button lets you collect it.

Scavenging from Containers – Some backpacks and wicker baskets can yield Great Mullein when looted. In practice, players often combine this with resource runs in hotspots where these containers spawn frequently.

Buying from Celeste – If you’re low on time or just want a guaranteed supply, you can purchase it directly from the merchant. For players who don’t have easy access to farm locations, buying arc raiders items online, including Great Mullein, is another reliable option.

How Does Harvesting Work?

When harvesting, it’s not just about walking up and pressing a button. Timing and positioning matter:

Plant respawn: Great Mullein plants respawn at predictable intervals, usually between 10–15 minutes. Experienced players mark these locations mentally or on a shared map.

Group farming: If you’re in a squad, spreading out across different plant clusters is more efficient. Everyone gets resources without crowding the same plant.

Inventory management: Each plant gives one unit per interaction. Since the stack size is only 15, make sure your inventory can hold multiple stacks before farming in bulk.

From experience, a good harvest loop in a moderate area yields about 20–25 units in 15–20 minutes if you optimize your route.

Crafting Tips

Great Mullein is versatile, but its main use is crafting medical items. A few practical points:

Refiner vs Medical Lab: The Refiner is for processing larger quantities at once, particularly for Antiseptic. The Medical Lab is better for Herbal Bandages. In practice, if you need both, plan a batch craft session where you use each station for its intended recipes.

Traveling Tinkerer: If you’re out in the field, the Traveling Tinkerer skill allows you to craft Herbal Bandages on the go. This is useful for solo players or when running resource-heavy missions where returning to a lab is time-consuming.

Stockpiling: Even if you don’t need the medkits immediately, crafting in advance and storing them in a chest can save time during missions.

Recycling and Salvaging

Great Mullein isn’t just for crafting; you can also use it as a recycling or salvaging resource:

Recycling: Returns 2× Assorted Seeds per unit. This is useful if you want to grow more plants in your farm plots.

Salvaging: Gives 1× Assorted Seeds. In practice, salvaging is slightly less efficient than recycling, but it’s often convenient if you need seeds while exploring without access to a recycling station.

Players often combine recycling with farm expansion, creating a self-sustaining loop for Great Mullein farming.

Best Practices for a Great Mullein Farm

Based on common player behavior, here’s what works:

Identify a cluster of plants: Topside areas often have 3–5 plants in a small zone. Stick to these zones rather than running around randomly.

Rotate with your team: If you play in a squad, assign different clusters to each player. This avoids respawn conflicts.

Carry a portable crafting kit: With the Traveling Tinkerer skill, you can craft Herbal Bandages on the move. It saves inventory space and allows you to convert resources instantly.

Keep an eye on your weight and stack limits: You’ll often reach your carrying capacity before your crafting station. Prioritize harvesting enough Great Mullein for your next crafting session.

Combine with other resources: While farming, pick up additional materials like Durable Cloth and Fabric. This reduces the number of trips back to your base.

Common Mistakes to Avoid

Ignoring respawn times: Harvesting the same plant repeatedly before it respawns wastes time.

Overloading inventory: Since stacks are small, carrying more than necessary can block new materials from being picked up.

Focusing only on quantity: High-volume farming is not always efficient. Sometimes crafting on the go or combining with scavenging nets more usable items in the same time.


A successful Great Mullein farm is a mix of preparation, timing, and efficient crafting. Whether you harvest manually, scavenge containers, or buy from merchants, the goal is the same: have a steady supply for crafting medical items. Experienced players know that combining field harvesting with batch crafting at labs gives the best balance of efficiency and resource management.

With the right approach, Great Mullein can support long missions without constant trips back to base. Keeping a small stockpile of Herbal Bandages and Antiseptic ensures you’re ready for any Topside encounter.

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